FRONTLINE Combo Spot on Dog M 1x1 pipette 1.34ml

For dogs and puppies older than 8 weeks: 
For use against flea infestations, with fleas or fleas only, with ticks and / or strains.

• Cleansing (Ctenocephalides spp.) The insecticidal effect against adult flea infestation lasts for up to 8 weeks. Preventing flea growth by suppressing egg development (ovicidal effect), larvae and their developmental stages (larvicidal effect) developed from adult egg fleas for up to 8 weeks after application.
• Elimination of ticks (Ixodes ricinus, Dermacentor variabilis, Rhipicephalus sanguineus). The product has a sustained acaricidal effect for up to 4 weeks against ticks (documented by the results of experimental studies)
• Elimination of lice (Trichodectes canis). The product can be used as part of a treatment strategy for flea binge allergy (FAD)

COMPOSITION
Each pipette of 1.34 ml contains: Fipronilum 134.00 mg, (S) - Methoprene 120.60 mg 

Route of administration: external application to the skin. 

Dosage:
One pipette of 1.34 (M) ml for a medium sized dog weighing between 10 and 20 kg. 

This provides the minimum recommended dose of 6.7 mg / kg fipronil and 6 mg / kg (S) -methoprene. Due to the absence of studies on the safety of the product, the minimum interval between applications is 4 weeks. Method of administration: Hold the pipette upright and break the tip. Double-tap the tapered portion of the pipette to make sure the content stays on the main pipette. Unfold the animal's coat in the area of ​​the base of the neck before the blades until the skin is visible. Put the tip of the pipette on the skin and press it several times so that the contents are emptied directly into the skin in one place. 

CONTRAINDICATION
Due to the lack of adequate data on the use of the product in the youngest age groups, do not apply to puppies under 8 weeks of age and / or weighing less than 2 kg. 
Do not use in rabbits where unwanted reactions may occur leading to death. 
Do not apply to sick animals (eg systemic illnesses, fever ...) or animals in convalescence. The product is intended for dogs. Do not use in cats could cause overdose. 

SIDE EFFECTS
Transient cutaneous skin reactions at the site of application (skin color change, local hair loss, itching, redness) and total pruritus or loss of hair have been reported between rarely occurring adverse reactions following use. Excessive salivation, reversible nerve symptoms (increased sensitivity to stimulation stimuli, depression, other nerve symptoms), vomiting or respiratory symptoms have also been observed after use. 

If a louse has occurred, a short period of excessive salivation may occur as a reaction induced mainly by the properties of the carrier. Warn overdose. 

If you notice any serious side effects or other effects not mentioned in this leaflet, please inform your veterinary surgeon. 

NOTICE
It is important to ensure that the preparation is applied to a place where the animal can not be licked and, after application, prevent the animals from licking each other. Swimming / soaking in water within 2 days after application of the product and more frequent bathing than once a week is not recommended due to the fact that no study has been conducted to determine how bathing affects the efficacy of this product. Emollient shampoos may be used before treatment but shorten the duration of action against fleas to approximately 5 weeks when used once weekly after application. Bathing each week using a 2% chlorhexidine medicated shampoo did not affect flea efficacy during a 6-week study.

Individual ticks can be attached. Therefore, transmission of infectious diseases can not be ruled out if conditions are unfavorable. Fleas in domestic animals often attack animal cages, places where the animal sleeps and rests, such as carpets and home furnishings, which should be regularly treated with suitable insecticides and cleaned with a vacuum cleaner in case of massive infestation and at the beginning of protective measures. 

WARNING
This product may cause irritation of mucous membranes, skin and eyes. Avoid contact of this product with your mouth, skin and eyes. 

Animals or people with known hypersensitivity to insecticides or alcohol should not come into contact with Frontline Combo Spot On Dog. Be careful not to touch the fingers with the contents. If it occurs, wash your hands with soap and water.

In case of accidental eye contact, rinse the eye with clean water. Wash hands after use. Do not manipulate with treated animals and prevent children from playing with them until the application has dried out. It is therefore recommended not to treat animals during the day, but early in the morning, and not allow freshly treated animals to sleep with their owners, especially children. 

Do not smoke, drink or eat during application. 

The FRONTLINE COMBO® package insert contains complete information on use, including warnings and warnings. Always read the package leaflet and follow the instructions before using it.