Buscopan plus paracetamol 20 tablets

Buscopan plus Paracetamol 10 mg/ 500 mg film-coated tablets contain two active ingredients: Hyoscine-N-butyl bromide has an antispasmodic effect on the smooth muscles of the gastrointestinal tract, biliary tract and urinary tract and female genital organs; Paracetamol has a rapidly onset analgesic, antipyretic and anti-inflammatory effect.

Buscopan plus Paracetamol film-coated tablets are used for cramping pain in the gastrointestinal tract, biliary tract and urinary tract and female genital organs during menstruation.
Buscopan plus Paracetamol film-coated tablets are used in adults and adolescents aged 12 years and older

If you don't feel better or even worse after 3 days, contact your doctor.

Contraindications

Do not take Buscopan plus Paracetamol,

• if you are allergic to hyoscine N-butyl bromide, other bromides, paracetamol or any of the other ingredients of this medicine (listed in section 6);
• if you suffer from a certain form of muscle weakness (myasthenia gravis);
• if you have been diagnosed with an organically induced narrowing of the gastrointestinal tract or if there is a suspicion of this;
• if you have been diagnosed with a debilitating (paralytic) or mechanical intestinal obstruction (ileus). Symptoms include severe abdominal pain with a lack of bowel movements and/or nausea/vomiting;
• if you have a pathological enlargement of the colon;
• if your liver or kidney function is severely impaired;
• if you drink alcohol regularly or in large quantities (see "Buscopan plus paracetamol with food and drink").

Interactions

Other medicines
and Buscopan plus paracetamol Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines.

Interactions with paracetamol

Ask your doctor for advice before taking Buscopan plus Acetaminophen film-coated tablets if you are taking any of the following medicines at the same time, as these medicines and paracetamol may affect each other's effects and side effects:
medicines that affect liver function, such as barbiturates (anaesthetics), phenobarbital, phenytoin (medicines used to treat epilepsy), glutethimide (sleeping pills and sedatives), carbamazepine (medicines for the treatment of depressive disorders) or certain antibiotics (such as rifampicin) increase the liver-damaging effect of paracetamol – liver damage is then already possible by otherwise harmless doses. This also applies to all other medicines for which possible liver damage is described and to alcohol abuse.
Salicylamide (anti-inflammatory painkiller) causes an increased damaging effect of paracetamol as a result of delayed excretion.
Probenecid (uric acid-lowering drug) reduces paracetamol excretion to about half. If you are taking probenecid at the same time, your doctor will reduce the dose of paracetamol accordingly.
The harmful effect of chloramphenicol (certain antibiotic = medicine for infections) is increased by a delayed excretion of chloramphenicol.
Paracetamol may increase the risk of bleeding in patients taking warfarin and other vitamin K antagonists (medicines used to thin the blood).
Taking flucloxacillin (antibiotic) at the same time can lead to acidification of the blood and the body.
Colestyramine (a medicine used to lower cholesterol) reduces the absorption of paracetamol.
Medicines that slow down gastric emptying can lead to reduced absorption and, as a result, to a delayed onset of the effects of paracetamol. Drugs that cause acceleration of gastric emptying (for example, metoclopramide or domperidone for vomiting and nausea) increase the absorption of paracetamol.
The concomitant use of paracetamol and zidovudine (medicines for HIV infection) makes a reduction in the number of white blood cells (neutropenia) more likely and should only be done on medical advice.

Interactions with hyoscine N-butyl bromide

Ask your doctor for advice before taking Buscopan plus Paracetamol film-coated tablets if you are taking any of the following medicines at the same time, as the effects of these medicines may be enhanced by hyoscine N-butyl bromide:

• antihistamines (for allergic diseases);
• Amantadine-containing medicines (for Parkinson's disease);
• Quinidine- or disopyramide-containing medicines (for cardiac arrhythmias);
• tri- and tetracyclic antidepressants (for depression);
• other anticholinergics (e.g. tiotropium, ipratropium – for breathing difficulties or atropine-like agents);
• antipsychotics (for psychosis);
• β sympathomimetics (for difficulty breathing).

You should also ask your doctor for advice if you are taking medicines to correct intestinal motility (e.g. medicines containing metoclopramide) at the same time as Buscopan plus paracetamol, as this may reduce the effect of both medicines.

Influencing laboratory tests Paracetamol may interfere with certain laboratory tests
used to determine uric acid levels and blood glucose levels.
Therefore, please inform your doctor about taking Buscopan plus Paracetamol film-coated tablets before laboratory tests.

Taking Buscopan plus paracetamol with food, drink and alcohol
Concomitant alcohol consumption increases the risk of liver damage at normally harmless doses of paracetamol and should therefore be avoided! This is especially true of alcohol abuse.

Pregnancy and breastfeeding If you are pregnant or breastfeeding, or if you think you may be pregnant or intend to become pregnant, ask your doctor or pharmacist for advice before taking this medicine.
Taking Buscopan plus paracetamol during pregnancy is not recommended.
The excretion of hyoscine N-butyl bromide, one of the active ingredients of Buscopan plus paracetamol, into breast milk has not been studied. Therefore, the use of Buscopan plus paracetamol during breastfeeding should be avoided as a precaution.

Driving and using machines No studies have been conducted on the effects on the ability to drive and use machines
. However, if taken correctly, no impairments are to be expected in active participation in road traffic or in the operation of machines.

Application

Always take this medicine exactly as described in this leaflet or exactly as your doctor or pharmacist has told you. Check with your doctor or pharmacist if you're not sure.
The recommended dose for adults and adolescents over 12 years of age is 3 film-coated tablet 1 times a day. If necessary, a single dose of 2 film-coated tablets can be given.
Do not exceed a maximum daily dose of 4 film-coated tablets. The time interval should be at least 8 hours until the next application.

For oral use.
The film-coated tablets should be swallowed whole with sufficient liquid. The notch is not used to divide the tablet.

Special patient groups
Elderly patients The same dosage recommendations apply to elderly patients
.

Patients with impaired liver or kidney function
If you have a liver or kidney disorder, your doctor may prescribe a lower dose or recommend that you extend the dosing interval (the time interval between two doses). In case of severe disorders of liver or kidney function, Buscopan plus paracetamol film-coated tablets must not be taken.

Duration of
use Buscopan plus Paracetamol 10 mg/ 500 mg film-coated tablets should not be taken for more than 3 days without medical advice.
Please talk to your doctor or pharmacist if you have the impression that the effect of Buscopan plus Paracetamol film-coated tablets is too strong or too weak.

Use in children and adolescents
Buscopan plus Paracetamol 10 mg/ 500 mg film-coated tablets are not recommended for use in children under 12 years of age due to the high content of paracetamol. For adolescents, the dosage recommendations for adults apply.

Side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them.
In studies with Buscopan plus paracetamol, the following side effects have been observed:

Uncommon (may affect up to 1 in 100 people):

• Nausea (as a sign of a hypersensitivity reaction)
• skin reactions (e.g. hives, itching)
• Xerostomia
• Disturbance of sweat gland activity

Rare (may affect up to 1 in 1,000 people):

• Redness of the skin
• Drop in blood pressure, including shock (as a sign of a hypersensitivity reaction)
• Accelerated heartbeat

Very rare (may affect up to 1 in 10,000 patients):

• Hives, rash

Not known (frequency cannot be estimated from the available data):

• Changes in blood counts such as a decrease in platelets (thrombocytopenia) or white blood cells (leukopenia, neutropenia, agranulocytosis), breakdown of red blood cells that can lead to pale yellow complexion, weakness and shortness of breath (haemolytic anaemia), or reduction of all blood cells (pancytopenia)
• shortness of breath, disorders or failure of the cardiovascular system (anaphylactic reactions, anaphylactic shock), drug eruption, other hypersensitivity reactions (including sudden swelling of the skin and/or mucous membranes – especially in the facial area, if the nose, larynx and tongue are involved, possibly with shortness of breath and difficulty swallowing [angioedema], hives, rash, severe inflammatory skin diseases with blistering and Skin peeling [Steven Johnson syndrome, toxic epidermal necrolysis, acute generalized exanthematous pustulosis])
• Shortness of breath due to spasm of the muscles of the bronchi (more common in people with allergy to anti-inflammatory painkillers and rheumatism drugs [NSAIDs])
• Inflammation of the liver, which can lead to liver failure
• Increase in certain liver values
• Urinary retention

Taking high doses of paracetamol, even prolonged or long-term use, can lead to kidney dysfunction and severe liver damage (see "Warnings and Precautions").

Composition

The active ingredients are:
10 mg hyoscine-N-butyl bromide and 500 mg paracetamol per film-coated tablet

The other ingredients are:Tablet core: ethyl cellulose, colloidal anhydrous silica, magnesium stearate, corn starch, microcrystalline cellulose, carmellose sodium, tablet coating:
dimethicone, hypromellose, macrogol 6000, methacrylic acid-methyl methacrylate copolymer, talc,
titanium dioxide (E171)

Your order will be shipped within 3-4 business days